Participate in Research

The following Research Studies are seeking candidates, please visit the links below, and contact these organizations for more information.

Center for Neuroscience and Regenerative Medicine’s (CNRM) clinical research studies include both military and civilian participants, with or without traumatic brain injury (TBI, also known as concussion) or posttraumatic stress (PTS), who are 18 and older. Those with military experience can be active or reserve component, veterans or retirees. We welcome those who have symptoms of TBI/concussion or PTS, as well as family and friends to participate, and together we can make a difference. Follow this link or call 1-855-824-2676

http://www.cnrmstudies.org/participation#.VrUTzI-cHIU

Learn more about current trials at Cleveland Clinic Lou Ruvo Center for Brain Health:

Cleveland: 216.445.9009 or 844.767.8629
Email: cbhresearch@ccf.org

Las Vegas: 855.568.7886
Email: brainhealth@ccf.org

You could do something today to make a difference for your family and your community. At your next visit, ask your doctor if clinical trials are right for you.

Actively Recruiting: These studies are currently seeking participants

Center for Brain Health Biobank

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Those diagnosed with neurodegenerative disease (e.g. Alzheimer’s disease, Parkinson’s disease), those considered at-risk for neurodegenerative disease and those considered healthy
Study Type: Observational (no drug treatment)
Learn more


COBRE

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Normal, Alzheimer’s; Parkinson’s, 55-90 years of age
Study Type: Observational (no drug treatment)
Learn more
Purpose: A National Institutes of Health (NIH)-funded study to enhance our understanding of aging across diverse populations


Diagnose CTE

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: NFL or college football players; 45-74 years of age
Study Type: Observational (no drug treatment)
Learn more

 


Exert

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Mild cognitive impairment (MCI), 65-89 years of age
Study Type: Interventional (Exercise)
Learn more
Purpose: Can exercise slow the progression of memory loss in people with MCI?


Generation I

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Has APOE HZ gene, 60-75 years of age
Study Type: Interventional (Oral Medication/Vaccine)
Purpose:  Can a medication reduce genetic risk of developing memory problems?
Learn more


Healthybrains.org

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: All
Study Type: Registry (database of prospective research participants)
Learn more
Purpose: An online community of individuals interested in receiving a free self-assessment and learning more about their brain health, with the opportunity to receive a monthly newsletter and join a database of potential research volunteers.


Mission AD

Location:  Las Vegas and Cleveland
Status: Active – Recruiting
Eligibility: Mild cognitive impairment (MCI) due to Alzheimer’s, early AD, 50-85 years of age
Study Type: Interventional (Oral Medication)
Learn more
Purpose: Can a pill that reduces amyloid plaque buildup in the brain help individuals with mild memory problems?


TANGO

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Mild cognitive impairment (MCI)/Mild Alzheimer’s, 50-80 years of age
Study Type: Interventional (Infusion)
Learn more
Purpose:  Can the first study to use an anti-tau protein infusion slow the decline of cognitive and functional impairment in people with mild cognitive impairment (MCI)?

Government Data Base of Clinical Trials

https://clinicaltrials.gov/ct2/results?cond=Chronic+Traumatic+Encephalopathy&Search=Apply&recrs=a&age_v=&gndr=&type=&rslt=

 For emergency brain donation matters, call the 24 hour emergency donation pager at 617.992.0615.

BRAIN DONATION REGISTRY

Donating one’s brain to research is one of the most precious gifts an individual can make. Brain donation helps researchers understand the consequences of repetitive brain trauma by allowing close examination of any injuries or disease processes.

All adults, with or without a history of sports participation or military service, are eligible to register as brain donors. Registrants receive a brain donor wallet card, as well as information on the brain donation process. Donated tissue is examined by a team of doctors who arrive at a consensus diagnosis which is communicated to next of kin. All expenses associated with donation and analysis are handled by the brain bank – there is no cost to donors or family members.

Location: International
Seeking: Athletes and military veterans throughout the United States may pledge to donate their brains and spinal cords upon their death to look for evidence of damage and disease
Goal: Understand CTE, share tissue with researchers around the world to advance knowledge
Contact: To discuss imminent brain donation, please call the 24 hr. emergency donation cellphone/pager at 617.992.0615.. Sign up here to join the brain donation registry with the option to receive a wallet card.

JOIN THE RESEARCH REGISTRY

The research registry was created to assist in recruiting participants for research at institutions across the United States, including the Boston University CTE Center. When you join this registry, you will receive communications from us that will keep you updated on new research programs for which you may be eligible. Click here to join.

We are proud to support the following studies currently underway across the country. To learn more, please click on the links associated with each study.

LEGEND (LONGITUDINAL EXAMINATION TO GATHER EVIDENCE OF NEURODEGENERATIVE DISEASE)

Seeking: Current and former athletes of all levels throughout the US and Canada for yearly telephone interview
Goal: Learn about risk factors for concussions and CTE
Learn more here.

DIAGNOSE CTE RESEARCH PROJECT (DIAGNOSTICS, IMAGING, AND GENETICS NETWORK FOR THE OBJECTIVE STUDY AND EVALUATION OF CHRONIC TRAUMATIC ENCEPHALOPATHY)

Seeking: Former NFL players, former college football players, and non-contact athlete control participants between the ages of 45 and 74 will be recruited for a three day study visit at one of four locations.
GoalThe DIAGNOSE CTE Research Project is a multi-center, multi-disciplinary, 7-year, longitudinal study designed to develop and refine methods of diagnosing Chronic Traumatic Encephalopathy (CTE) during life and to examine risk factors for CTE. The study will not be providing a diagnosis or treatments to participants. Funded by the National Institute of Neurological Disorders and Stroke.
Learn how to participate here or contact Taylor Platt at diagnose@bu.edu or 617-414-1193.
Click here to visit the DIAGNOSE CTE Research Project website.

HOPE CTE STUDY (HEALTH OUTREACH PROGRAM FOR THE ELDERLY)

Location: Greater Boston
Seeking: Male and female subjects who are at least 50 years old, played a minimum of five years of football, MMA, boxing, rugby, soccer, or ice hockey, with two of those years occurring at the collegiate, semi-professional, or professional levels. Participants will have a two-day visit once a year to the BU School of Medicine to participate in a variety of tests, including a neurologic exam, memory and cognitive tests, mood and behavior questionnaires, a blood draw, and an MRI scan.
Goal: The HOPE Chronic Traumatic Encephalopathy (CTE) study is designed to develop methods of diagnosing CTE during life. This is an extension of the Health Outreach Program for the Elderly (HOPE) Study of the Boston University Alzheimer’s Disease Center.

Interested in participating? Contact Alyssa Phelps at phelps@bu.edu or 617-358-6545.