The following Research Studies are seeking candidates, please visit the links below, and contact these organizations for more information.

If you are 18 years or over, you can help the Brain Health Registry speed up the discovery of treatments for Alzheimer’s, Parkinson’s, depression, PTSD, and other brain disorders. It takes just a few minutes to get started. For most people, participation takes less than three hours per year. The steps are easy to follow:

Join the Brain Health Registry here


Are you a former NFL player, former Division-I collegiate football player, or a former collegiate athlete who has never played organized contact sports?

The CLF Research Registry comprises the Brain Donation Registry (BDR) and Clinical Research Registry (CRR). You may sign up for one or both.

Center for Neuroscience and Regenerative Medicine’s (CNRM) clinical research studies include both military and civilian participants, with or without traumatic brain injury (TBI, also known as concussion) or posttraumatic stress (PTS), who are 18 and older. Those with military experience can be active or reserve component, veterans or retirees. We welcome those who have symptoms of TBI/concussion or PTS, as well as family and friends to participate, and together we can make a difference. Follow this link or call 1-855-824-2676

Are you suffering from Post-Concussion Syndrome (PCS) or possible Chronic Traumatic Encephalopathy (CTE)? Is a family member suffering from PCS or possible CTE? Join this study to help researchers understand how brain trauma affects patients’ and caregivers’ lives.Learn more about current trials at Cleveland Clinic Lou Ruvo Center for Brain Health:

Oxford Brookes -PCS TES CTE – May 2020

Experiencing problems with: Thinking? Memory? Concentration?
Study seeks participants who have had one or more
Traumatic Brain Injuries who can travel to Boston.

LED_Concussion_Legacy_Flyer (002)

Actively Recruiting: These studies are currently seeking participants

Project S.A.V.E. 

Location:  Boston & San Francisco
Status: Active – Recruiting
Eligibility: Former contact sport athletes over the age of 50
Learn more

Operation Synchrony

Location: Southern California

Seeking: Researchers at Wave Neuroscience and Brain Treatment Centers are seeking 120 post-9/11 military service members and Veteran participants. This outpatient program is completely FREE, due to the additional support of our friends at the Wounded Warrior Project, and focuses on treating the mental health of military service members and Veterans. Wave Neuroscience empowers non-pharmaceutical, non-invasive EEG guided neuromodulation to try to aid in better sleep, better focus, better mood, better emotional regulation and will improve your overall cognition.

Goal: The purpose of this study is to track changes in symptoms of Persistent PCS, PTSD, Quality of Life Enjoyment, and Incidents and Adverse Behavior in post-9/11 military service members and Veterans.

Interested in participating? Visit


Center for Brain Health Biobank

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Those diagnosed with neurodegenerative disease (e.g. Alzheimer’s disease, Parkinson’s disease), those considered at-risk for neurodegenerative disease and those considered healthy
Study Type: Observational (no drug treatment)
Learn more


Head Impact & Trauma Surveillance Study
Entirely online at
Seeking: Anyone aged 40+ who played soccer or tackle football at any level – youth, high school, college or pro/elite. Participation is a fully-online survey that includes questionnaires on sports participation, medical history and behavior and mood, and brain games. It only takes approximately two hours to complete, and can be completed at any time and over several days, if desired. Participants are then asked to take a follow up assessment online one year later.
Goal: The major goal of HITSS is to answer questions about risks of developing later life brain health issues from repetitive head impacts in contact sports. To learn more or to participate click here.




Location:  Las Vegas
Status: Active – Recruiting
Eligibility: Normal, Alzheimer’s; Parkinson’s, 55-90 years of age
Study Type: Observational (no drug treatment)
Learn more
Purpose: A National Institutes of Health (NIH)-funded study to enhance our understanding of aging across diverse populations

Location:  Las Vegas
Status: Active – Recruiting
Eligibility: All
Study Type: Registry (database of prospective research participants)
Learn more
Purpose: An online community of individuals interested in receiving a free self-assessment and learning more about their brain health, with the opportunity to receive a monthly newsletter and join a database of potential research volunteers.

Molecular Imaging of Brain Injury and Repair in NFL Player

Location: Baltimore
Seeking: Researchers at Johns Hopkins are seeking former NFL players who played for two or more seasons and whose last season was within the last five years. Participants must be between 25 and 40 years old and have no history of psychiatric disease. Qualified participants will undergo a PET scan, an MRI scan, and an optional lumbar puncture. Those completing the study will receive compensation for time and travel to Baltimore.
Goal: The purpose of this study is to track markers of injury and repair, provide data to analyze concussions, determine the severity of the effects, and determine the overall long term health impact on the players.

Interested in participating? Contact Dr. Jennifer Coughlin at or 443.287.4701.

Government Data Base of Clinical Trials

 For emergency brain donation matters, call the 24 hour emergency donation pager at 617.992.0615.


Donating one’s brain to research is one of the most precious gifts an individual can make. Brain donation helps researchers understand the consequences of repetitive brain trauma by allowing close examination of any injuries or disease processes.

All adults, with or without a history of sports participation or military service, are eligible to register as brain donors. Registrants receive a brain donor wallet card, as well as information on the brain donation process. Donated tissue is examined by a team of doctors who arrive at a consensus diagnosis which is communicated to next of kin. All expenses associated with donation and analysis are handled by the brain bank – there is no cost to donors or family members.

Location: International
Seeking: Athletes and military veterans throughout the United States may pledge to donate their brains and spinal cords upon their death to look for evidence of damage and disease
Goal: Understand CTE, share tissue with researchers around the world to advance knowledge
Contact: To discuss imminent brain donation, please call the 24 hr. emergency donation cellphone/pager at 617.992.0615.. Sign up here to join the brain donation registry with the option to receive a wallet card.


The research registry was created to assist in recruiting participants for research at institutions across the United States, including the Boston University CTE Center. When you join this registry, you will receive communications from us that will keep you updated on new research programs for which you may be eligible. Click here to join.

We are proud to support the following studies currently underway across the country. To learn more, please click on the links associated with each study.


Seeking: Current and former athletes of all levels throughout the US and Canada for yearly telephone interview
Goal: Learn about risk factors for concussions and CTE
Learn more here.


Seeking: Former NFL players, former college football players, and non-contact athlete control participants between the ages of 45 and 74 will be recruited for a three day study visit at one of four locations.
GoalThe DIAGNOSE CTE Research Project is a multi-center, multi-disciplinary, 7-year, longitudinal study designed to develop and refine methods of diagnosing Chronic Traumatic Encephalopathy (CTE) during life and to examine risk factors for CTE. The study will not be providing a diagnosis or treatments to participants. Funded by the National Institute of Neurological Disorders and Stroke.
Learn how to participate here or contact Taylor Platt at or 617-414-1193.
Click here to visit the DIAGNOSE CTE Research Project website.

Athlete Brain Health & Aging Study

Athlete Brain Health & Aging Study
Location: National
Seeking: Former NFL players, former Division I college football players, and former male college athletes who never played contact sports.
Goal: The purpose of this research study is to use research to improve health and support the well-being of men of all ages. Previous research on brain health has focused on biological factors, but we know that a person’s psychology, personal beliefs, social groups, and surroundings are also fundamental for brain wellness. These psychosocial factors vary for different groups, such as among Black, White, and Latino men, but more must be understood about how these factors affect brain health. The goal of this study is to discover the effects these important factors have on brain aging to support people like you, your friends, family, and community members.

Interested in participating? Click here to learn more.


Health Outreach Program for the Elderly
Location: Greater Boston
Seeking: Male and female subjects who are at least 50 years old, played a minimum of five years of football, MMA, boxing, rugby, soccer, or ice hockey, with two of those years occurring at the collegiate, semi-professional, or professional levels. Participants will have a two-day visit once a year to the BU School of Medicine to participate in a variety of tests, including a neurologic exam, memory and cognitive tests, mood and behavior questionnaires, a blood draw, and an MRI scan.
Goal: The HOPE Chronic Traumatic Encephalopathy (CTE) study is designed to develop methods of diagnosing CTE during life. This is an extension of the Health Outreach Program for the Elderly (HOPE) Study of the Boston University Alzheimer’s Disease Center.

Interested in participating? Contact or 617.358.6545.