CTE Research

Below are some articles for further reading about research on CTE. Some may require the Adobe Acrobat reader plugin.


Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts

Bodychecking experience and rates of injury among ice hockey players aged 15–17 years

 

Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy

Inflammation and CTE are linked

 

Toxic Protein, Linked to Alzheimer’s and Other Neurodegenerative Diseases, Exposed in New Detail

 

This study suggests that repeated head injuries damage the part of the brainstem region that is important for sleep.

https://www.nia.nih.gov/news/sleep-disturbances-linked-abnormal-deposits-certain-proteins-brain

Study links youth football to greater risk of later health problems

https://www.bostonglobe.com/sports/2017/09/19/study-links-youth-football-greater-risk-later-health-problems/UF3vWIAraotnJnbU8o8TDP/story.html

Sub-concussive blows can cause brain injury, says Trinity research

https://www.irishtimes.com/sport/rugby/sub-concussive-blows-can-cause-brain-injury-says-trinity-research-1.3245891

New Study Identifies Class of Drugs That Removes Abnormal Proteins in Brain and Improves Memory in Mice :

http://www.businesswire.com/news/home/20151221006111/en/Study-Identifies-Class-Drugs-Removes-Abnormal-Proteins

New antibody treats traumatic brain injury and prevents long-term neurodegeneration…

http://medicalxpress.com/news/2015-07-antibody-traumatic-brain-injury-long-term.html

Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from CTE

https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-018-1312-4

Unique Coalition To Launch Human Stem Cell Trial For Traumatic Brain Injury :

http://www.prnewswire.com/news-releases/unique-coalition-to-launch-human-stem-cell-trial-for-traumatic-brain-injury-300266688.html

The Future of Detecting Brain Damage in Football

https://www.theatlantic.com/health/archive/2017/09/football-brain-injury-chronic-traumatic-encephalopathy/540459/

Effects of Subconcussive Head Trauma on the Default Mode Network of the Brain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238241/

Concussions linked to academic struggles in UW-Madison students

http://host.madison.com/wsj/news/local/health-med-fit/concussions-linked-to-academic-struggles-in-uw-madison-students/article_2de58ab3-2838-56d1-ac8e-6957246717a8.html?utm_medium=social&utm_source=facebook&utm_campaign=user-share

CTE Detected on NFL Player’s Tau Scan

http://www.medpagetoday.com/Neurology/HeadTrauma/60475

Chronic Traumatic Encephalopathy: Historical Origins and Current Perspective

http://www.annualreviews.org/eprint/zT2NHRNBhXyJXuD6vqkd/full/10.1146/annurev-clinpsy-

Collision Course: A Spectator report on the science of hard head knocks

https://www.thespec.com/news-story/7525066-collision-course-the-hard-science-of-hard-knocks/#pq=lhxYyp

Alzheimer’s and Concussion-Related CTE May Spread in the Brain Via Common Mechanism

http://www.ucsf.edu/news/2016/12/405096/alzheimers-and-concussion-related-cte-may-spread-brain-common-mechanism

Brain Scan a leap forward for CTE Research

http://www.nydailynews.com/sports/i-team/new-brain-scan-leap-cte-research-article-1.2636640?cid=bitly

Inflammatory insults and mental health consequences: does timing matter when it comes to depression?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937234/

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

https://academic.oup.com/brain/article/141/2/422/4815697

Apolipoprotein E Epsilon 4 Genotype, Mild Traumatic Brain Injury, and the Development of Chronic Traumatic Encephalopathy

http://www.mdpi.com/2076-3271/6/3/78/htm

Studying PSP May Provide Clues to CTE

http://www.scientificamerican.com/article/obscure-disease-may-offer-backdoor-to-new-treatments-for-alzheimer-s-and-other-killers/

Blood Test Identifies Concussion-Related Brain Disorder

http://www.newsmax.com/t/health/article/716689

The neuropathology of sport

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255282/

Study author claims to find ‘piece of the puzzle’ in diagnosing CTE in living patients

http://www.tsn.ca/study-author-claims-to-find-piece-of-the-puzzle-in-diagnosing-cte-in-living-patients-1.469792#pq=08ZXiw

Report from the First NIH Consensus Conference to Define the Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy

http://www.ninds.nih.gov/research/tbi/ReportFirstNIHConsensusConference.htm

Football findings suggest concussions caused by series of hits

http://www.purdue.edu/newsroom/research/2012/120202NaumanFootball.html

Brain enzyme could prevent Alzheimer’s, neurodegenerative disease

http://www.medicalnewstoday.com/articles/310696.php

Vaccine developed by Australian and US researchers may reverse dementia and Alzheimer’s

http://www.ibtimes.com.au/alzheimers-breakthrough-vaccine-developed-australian-us-researchers-may-reverse-dementia-alzheimers

Meet the New Progressive Tauopathy: CTE in Athletes, Soldiers

Cleveland Clinic Lou Ruvo Center for Brain Health CTE Conference Series

(http://www.alzforum.org/new/detail.asp?id=3325)

By Gabrielle Strobel

ArticleWhen autopsies of football stars and wrestlers who had committed suicide touched off a storm of media coverage some years ago, the initial story was one of concussions putting athletes at risk for Alzheimer’s disease. Since then, however, the story has taken a sharp turn. Prompted by striking brain pathology in both contact sport athletes and military veterans, scientists are now defining a new disease. Called chronic traumatic encephalopathy (CTE), the underlying concept envisions a massive tauopathy that spreads from the site of impact throughout the brain during the months and years after hits to the head. In other words, a progressive disease that stands apart from the known manifestations of traumatic brain injury (TBI). On 30 September to 1 October 2012, at the first research conference dedicated exclusively to CTE, scientists promulgated the idea that, of the estimated 1.7 million people who sustain mild TBIs in the U.S. every year, an untold number do not recover, nor do they live with the chronic, stable impairment that is sometimes called post-concussion syndrome. Instead, they develop a discrete secondary tauopathy that worsens with age and eventually leads to dementia or parkinsonism if the person survives long enough. Emerging research hints that CTE may self-propagate from cell to cell, as do other tauopathies…

Download The Full PDF Article

 

LSU experiments with new technology to diagnose head injuries

Concussion Assessment Research and Education (CARE) Consortium, a $30 million alliance between the NCAA and the Department of Defense that will test an estimated 35,000 male and female college athletes and service academy cadets over a three-year period.

http://espn.go.com/blog/sec/post/_/id/105843/lsu-experiments-with-new-technology-to-diagnose-head-injuries

 

New Research Provides Link to Brain Trauma and Alzheimers and CTE